7 Reasons Women On GLP-1s Are Adding Type II Collagen For Joint Pain
They told you that losing the weight would take the pressure off your knees. You did the hardest thing you have ever done, and the stairs got worse. Here is what nobody explained, and why it is not your medication and not your fault.
Kirsten Chick, DPT
Orthopedic Physical Therapist · 3 min read
412 shares
REASON 01
Losing the weight took the load off your knees. It never rebuilt the thing carrying the load.
Everyone told you the same thing. Your doctor, every article, common sense. Get the weight off and your joints will thank you.
So you did it. Forty pounds. Sixty. Eighty. The hardest thing you have ever done, and it worked, and then you got out of bed one morning and your knee still hurt. Some mornings worse than before.
That is not disappointment. Losing weight genuinely does reduce the load going through the joint with every step, and that part helped. But load was only ever half of it. The other half is the structure carrying the load, and that structure was quietly thinning at the same time.
The scale moved. The scaffold didn't.
REASON 02
Both layers protecting your knee are built out of the same material
Picture your knee. Do not picture bone, picture what is wrapped around it.
The outer layer is the muscle. Quads, glutes, hamstrings. Their job is not just to move you, it is to absorb force every single time your foot hits the ground. The tendon tying them to bone is roughly 80% collagen.
The inner layer is the cushion inside the joint itself. Cartilage. Roughly 60% collagen.
One shortage, two places it shows up. Which is why the mornings got stiffer and the same dumbbells got heavier at the same time, and you never connected the two.
REASON 03
Three things are draining that collagen at once, and one of them is the weight loss itself
1. MenopauseOestrogen holds collagen in place, with receptors in cartilage, tendon and ligament. Women lose roughly 30% of their skin collagen in the five years after menopause. Your requirement went up, not down.
2. AgeCollagen production has been slowing since your mid twenties. You reach for something one morning and it is not there.
3. The weight loss itselfNot the medication. The eating. Appetite suppression is how the shot works, and it is also the lowest protein intake of your adult life. Collagen is built from protein.
Nobody hid this. Nobody was assigned it. No specialty owns a woman's joints while she loses seventy pounds at fifty-six.
You have been given the demand side of the equation and none of the supply side.
Walk more, lift, do the PT. That is all demand, and you cannot build with an empty materials yard.
See it in one look
So which of these actually reaches the scaffold?
Ibuprofen, gelsTurns the alarm down
SURFACE
GlucosamineOne target, mixed evidence
SURFACE
Beauty collagenType I & III only
SKIN & TENDON
Strength trainingDemand, with no supply
MUSCLE ONLY
Revive MixType I, II & III + vitamin C
THE CUSHION
Pain signal onlyReaches some tissueReaches the cartilage itself
REASON 04
Your cartilage is Type II. The bag in your cupboard is Type I & III.
Go and get it. Turn it around and read the back.
If it says Type I & III, and almost every one of them does, that product was formulated for skin, hair and nails. Your face and your knee are not built from the same collagen. It is a different molecule doing a different job in a different tissue.
So when you took it every morning for two months and your knees did absolutely nothing, that was not you being one of the people it does not work on.
And most of the Type II on the shelf was cooked before it ever reached you
Collagen is normally heated at the factory so it dissolves nicely in a cold glass of water. For Type I & III that is fine, it is how they are meant to be delivered.
For Type II it is the end of the story. Whole Type II works because the immune tissue lining your gut can still recognise the intact molecule. Cook it and there is nothing left to recognise. You are drinking an expensive amino acid.
Revive Mix uses whole, undenatured Type II. Never heated, never broken down.
REASON 06
Not one type. Type I, II and III, in a single scoop.
Look at the picture. The pinch on the left is 40 mg of whole Type II. The scoop on the right is 10 g of Type I & III peptides. Same product, same serving, and people always ask how the small one can matter.
Because they are doing different jobs. The 10 grams is bulk supply, raw material for tendon and connective tissue to build with, and more genuinely is more. The 40 mg is not supply at all. Whole Type II works through a small consistent daily exposure via your gut, and that pathway runs on consistency, not volume. Every published trial on it used 40 mg.
Beauty powders give you the scoop and no pinch. Joint capsules give you the pinch and no scoop. You need both, plus the vitamin C your body physically cannot assemble collagen without.
REASON 07
And you can test it against us in 8 weeks, with a number you write down yourself
You have two abandoned bags in a cupboard already. You have every right to assume this is the third.
So do not take our word for it. Take a measurement.
Go for a walk today and count how many steps you get before your joints start to complain. Write that number on the fridge. One scoop a day, then retest at week eight. If the number has not gone up, email us and send the bag back. It can be completely empty. We refund every penny.
Worst case you are out nothing but eight weeks you were going to spend stiff anyway.
Free US shipping. Cancel any time. 60 day empty bag refund.
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Real people. Real stories.
★★★★★Stairs one at a time was my normal. Now I come down them like a normal person and my knees keep quiet.
Gill · 6 weeks
★★★★★Week four I put my socks on standing up. I did not cry, but close.
Sandra · 4 weeks
★★★★★My hands worried me most. Jar lids, toothpaste caps, the dog's leash. They are all mine again.
Tara · 6 weeks
★★★★★I'm 45. HRT never touched the joint part. Six weeks on this and I get out of bed like a normal person.
Margaret W.
f1.4K commentsMost relevant
Linda DoyleSix months of glucosamine. Two bottles of turmeric. Nothing. My daughter found this and I rolled my eyes, then by week ten I was on the floor with my granddaughter and got up without thinking about it. That's the part I love. It was normal.
LikeReply10w👍❤️ 214
Bev MarchettiLinda how long before you noticed anything? I'm 3 weeks in and starting to wonder 😅
LikeReply9w👍 31
Linda DoyleHonestly nothing for the first fortnight. Mornings were the first thing to shift for me, around week 5. Stick with it.
LikeReply9w👍 18
Victoria MearsI went to Spain for two weeks and left the bag on the kitchen counter. By day nine my knees were talking to me again. I didn't really believe it was doing anything until I stopped 🙈
LikeReply7w👍❤️ 176
Sharron KeeleyMy husband noticed before I did. He said I'd stopped making the noise getting out of a chair 😂
LikeReply6w👍😆 143
Gloria MendelAn hour of morning stiffness down to about ten minutes by month three. I'm on Zepbound and nobody warned me my joints would get worse after losing 60lb, not better.
LikeReply5w👍 98
Rosa JarrettKneeling in the garden and getting back up without grabbing the fence. That's it. That's the review.
LikeReply4w👍❤️ 87
Straight answers
No. It is food derived protein and micronutrients. Nothing to stop, nothing to switch, no competition with your medication. Your prescription handled the weight. This is aimed at the body underneath it. Mention it at your next appointment as you would anything else you add.
What you bought was almost certainly Type I & III, formulated for skin and hair. Cartilage is predominantly Type II. Turn the old bag around, and if there is no whole, undenatured Type II on that label then nothing in it was ever aimed at your knee.
Because oestrogen is part of what holds collagen in place. There are oestrogen receptors in cartilage, tendon and ligament, so as oestrogen drops the collagen in that tissue drops with it. The most cited figure is roughly 30% of skin collagen lost in the first five years after menopause, and skin is just the collagen you can see. Your requirement went up at the same time your intake went down.
Nothing in the first two weeks, and we would rather tell you that now than have you quit at week three feeling misled. Morning stiffness is usually the first thing to shift, somewhere around week four to six. Stairs, floors and walking distance tend to land at two to three months.
One scoop into whatever you are already drinking. Unflavoured, 0g sugar, no capsules to swallow on a nauseous morning, no extra meal, no appetite required.
You should, and we would tell you to. But general dietary protein and whey do not carry the glycine and proline rich profile that connective tissue is specifically built from, and appetite suppression makes hitting even a basic protein target genuinely hard. This is additive to protein, not a replacement for it.
Anyone wanting fast pain relief, because this is not a painkiller. Anyone already scheduled for joint replacement. Anyone with inflammatory or autoimmune arthritis expecting it to treat the underlying disease. And vegetarians and vegans, because collagen is animal derived.
Email us within 60 days and we refund every penny. The bag can be completely empty. Nothing to post back, no form, no reason required.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Revive Mix is a dietary supplement and is not a substitute for medical advice. Speak to your healthcare provider about persistent joint pain, and before adding any supplement alongside prescription medication. Customer results shown are individual experiences and are not typical.
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Gill · 6 weeks
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